Subproject C04
Subproject C04
Analysis of Degenerative Motion Impairments through Integration of Empatho-Kinaesthetic Sensor Data in Biomechanical Human Models
Analysis of Degenerative Motion Impairments through Integration of Empatho-Kinaesthetic Sensor Data in Biomechanical Human Models
The goal of sub-project C04 is the best possible integration of empathokinesthetic sensor data into biomechanical models. C04 focuses on improving the simulation of human hand movement to find new biomarkers for specific diseases. This is done by including data generated from different sensors that measure position, acceleration, and muscle activity. Specifically, degenerative movement restrictions of the hand are recorded by EmpkinS and reference sensor technology. These data are then optimally integrated into the mathematical formulation of the optimal control problem depending on data type, measurement frequency, measurement uncertainty, etc. These simulations will help to understand many diseases such as inflammatory arthritis, so we are then able to predict impaired movements and find new biomarkers to monitor the disease continuously.
Eventually, these insights in optimal data inclusion can be applied to general human movement.
Contacts
Principal Investigators
Prof. Dr.-Ing. habil. Sigrid Leyendecker
Principal Investigator
Doctoral Candidates
Simon Heinrich, M. Sc.
Doctoral Candidate
Others
Additional Information
Publications
- Phutane U, Liphardt AM, Bräunig J, Penner J, Klebl M, Vossiek M, Kleyer A, Schett G, Leyendecker S, Tascilar K: Evaluation of Optical and Radar Based Motion Capturing Technologies for Characterizing Hand Movement in Rheumatoid Arthritis — A Pilot Study Sensors 2021
- Nitschke M, Marzilger R, Leyendecker S, Eskofier B, Koelewijn A: Change the direction: 3D optimal control simulation by directly tracking marker and ground reaction force data PeerJ (2023)
- Shanbhag J, Wolf A, Wechsler I, Fleischmann S, Winkler J, Leyendecker S, Eskofier B, Koelewijn A, Wartzack S, Miehling J: Methods for integrating postural control into biomechanical human simulations: A systematic review Journal of NeuroEngineering and Rehabilitation (2023)
- Schubert M, Sato Martin de Almagro R, Nachbagauer K, Ober-Blöbaum S, Leyendecker S: Discrete Adjoint Method for Variational Integration of Constrained ODEs and Optimal Control of Geometrically Exact Beam Dynamics Multibody System Dynamics (2023)
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